POSTED BY gene2know | Oct, 22, 2018 |

The term “sandwich generation” has recently been applied to families raising children, as well as being responsible for the care of their aging parents and grandparents. Beyond the complexities of their own healthcare, children and aging relatives often present multiple challenges to limited resources. Just as the family unit has been changing, so has the face of healthcare. In the recent past, there has been considerable confusion and uncertainty in the healthcare industry. Because of this more responsibility is being placed upon consumers to become more informed and involved in healthcare decisions for themselves and their families. However, the quality of decisions being made is dependent upon the nature of the information available. Modern genetic testing provides critical information previously unavailable. It serves as an additional invaluable resource for caregivers of aging relatives.

Aging & Declining Health

There are numerous consequences associated with the aging process, and multiple diseases and maladies are not uncommon. Often, they are simply a consequence of being on the planet for decades. Primary aging accounts for the changes that commonly occur in most people as they age, such as graying hair, loss of visual acuity, and etc. However, secondary aging occurs as a result of use, misuse, and abuse. Secondary aging varies greatly but is often a reflection of lifestyle and its impact on an individuals’ genetics. As secondary aging progresses, so do visits with healthcare providers, which can often result in a prescription meant to address the issue at hand.

More Than 30% take 3+ medications daily

In fact, research shows that over three quarters of the population are taking at least one prescription medication, and greater than thirty percent are taking three or more medications and/or supplements daily, with the vast majority of prescription medications being prescribed to patients aged 65 and over. Every year, dozens of prescription medications are approved by the FDA and available to the public. Beyond the prescription medications, there are hundreds of new supplements available without a prescription. Although a prescription is not required, many of these substances have an effect on the body. While some effects are beneficial, others may work against medications already being taken. Currently, the Gene2Know databases instantly compare over 50,000 medications, vitamins, and supplements for compatibility with their unique genetic profiles. Understanding their genetic profile helps reduce adverse drug events (ADE) that may result from taking multiple medications, vitamins, and supplements. Genetic profiles illustrate possible interactions between unique genetic profiles with multiple medications, vitamins, and supplements. This gives you the ability to know how your body may respond BEFORE wasting time and money on inappropriate or ineffective medications, vitamins, and supplements. Immediate access to the Gene2Know databases represents a tremendous resource to assist caregivers of aging relatives, with their Gene2Know profile allowing you to avoid what makes them sick.


Genetic Mapping & New Hope

In 2000, the Human Genome Project completed the mapping of the entire human genome. Completion of this monumental task meant that most of the genes had been identified and accounted for. However, there are some gaps in the function of single genes, as well as the function of multiple genes. The research continues to identify and categorize new patterns, and the Gene2Know databases are updated regularly to reflect these advances. As a result, basic information has now become useful knowledge due to rapid advances in technology. In the past, healthcare providers relied upon their experience and previous patients. Oftentimes, this amounted to a trial-and-error method of diagnosis, prescription and treatment. The recent development and access to an aging relative’s unique genetic profie allows for more valid and reliable diagnoses, prescriptions, and treatments. There is no more need for guesswork that could delay treatment, and no need for you, your aging relative, or healthcare providers to settle for not knowing as much as possible.

Before healthcare providers see you, they often want to know your history, and even your family history. In the past genetic testing required a prescription and was prohibitively expensive. The testing also required tissue samples, usually in the form of a blood test. Taken together, these factors presented significant obstacles and resistance to testing. Technology has now advanced so that an easy, convenient, and painless saliva sample is all that is necessary to obtain a genetic profile, and this sample collection method has overcome much of the resistance to genetic testing.

As a caregiver, obtaining the unique genetic profile for aging relatives puts you on the cutting edge. In the past, you may have been frustrated by being left out of critical healthcare decisions. A Gene2Know profile for your aging relative allows you to become an active, informed participant as part of your family’s “Treatment Team.” The mobile app provides instant access to their personal genetic profile reports*. You can assume more control by staying informed about their unique genetic profiles from the convenience of your smartphone. For any questions about their own personal history and lifestyle, you have instant access to the Gene2Know databases for immediate answers. Regardless of where you are, you can experience the speed and convenience of the mobile app and scanner. You have access to the mobile app at any time, day or night. The extensive Pharmocogenomic (PGx) databases are constantly being updated as more medications and supplements are being approved by the FDA. The convenient mobile app lets you scan products for relevant nutritional information. The mobile app can also forward your information directly to any of their healthcare providers keeping all members of the treatment team informed.

**Requires purchase of G2K PGx medication report

Sources: 
Introducing Pharmacogenomic decision support for medication risk assessment in people with polypharmacy. Liu, Jiazhen, Finkelstein, Joseph, 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2017 IEEE International Conference on.: 1803-1808 Nov 2017.

Pharmacogenomic-based medication risk assessment in people with polypharmacy. 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2017 IEEE International Conference: Nov 2017.

Incidence of Exposure of Patients in the United States to Multiple Drugs for Which Pharmacogenomic Guidelines Are Available. Samwald M; Xu H; Blagec K; Empey PE; Malone DC; Ahmed SM; Ryan P; Hofer S; Boyce RD, Plos One [PLoS One], ISSN: 1932-6203, 2016 Oct 20.

History repeats itself: the family medication history and pharmacogenomics. Smith TR; Kearney E; Hulick PJ; Kisor DF, Pharmacogenomics [Pharmacogenomics], ISSN: 1744-8042, 2016 May.

Aging, Genetic Variations, and Ethnopharmacology. Woods, Diana Lynn; Mentes, Janet C.; Cadogan, Mary; Phillips, Linda R. Journal of Transcultural Nursing, Jan2017.

Polymorphisms of pro-inflammatory genes and Alzheimer’s disease risk: A Pharmacogenomic approach. Candore, Giuseppina; Balistreri, Carmela Rita; Grimaldi, Maria Paola; Listì, Florinda; Vasto, Sonya; Chiappelli, Martina; Licastro, Federico; Colonna-Romano, Giuseppina; Lio, Domenico; Caruso, Calogero. In Functional Genomics of Aging III, Mechanisms of Ageing and Development. 2007.

 

 

 

 

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